Status:
COMPLETED
University of Wisconsin hMSC Cell Bank: Bone Marrow Donor Protocol
Lead Sponsor:
University of Wisconsin, Madison
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Graft Versus Host Disease (GVHD)
Acute Myocardial Infarction (AMI)
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
The objective of this protocol is to use established standard criteria and methods for the collection of hMSC (human mesenchymal stromal cells) from healthy bone marrow donors. The hMSC collected from...
Detailed Description
Cell banks will be manufactured and cellular products used for future translational or clinical research.
Eligibility Criteria
Inclusion
- Age 18 to 35 years
- Willingness to provide written informed consent
Exclusion
- Presence of risk factors for or clinical evidence of Human immunodeficiency virus (type 1 and 2), Hepatitis B, Hepatitis C, Human T-lymphotrophic virus (type I and II), Human transmissible spongiform encephalopathy (including Creutzfeldt-Jakob disease) treponema pallidum,
- Presence of communicable disease risk associated with xenotransplantation.
- Test positive for Human immunodeficiency virus (type 1 and 2), Hepatitis B, Hepatitis C, Human T-lymphotrophic virus (type I and II), cytomegalovirus (CVM), West Nile Virus, treponema pallidum.
- Use of investigational drug within 30 days or 5 half lives which ever is longer. Use of investigational implanted device.
- History of malignancy.
- Pregnancy
- In the opinion of the hematologist or the investigator, a condition that compromises the ability of the donor to safely provide BM donation.
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT01463475
Start Date
September 1 2011
End Date
December 1 2013
Last Update
December 4 2014
Active Locations (1)
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1
University of Wisconsin-Madison
Madison, Wisconsin, United States, 53792