Status:

WITHDRAWN

Non-Inferiority Trial Comparing Eurofarma's Experimental Product Saccharomyces Boulardii Versus Floratil® in the Prevention of Antibiotic-Associated Diarrhea

Lead Sponsor:

Eurofarma Laboratorios S.A.

Conditions:

Antibiotics

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

The study's objective is to evaluate the efficacy and safety of two formulations for the prophylactic treatment of diarrhea in subjects using antibiotics.

Eligibility Criteria

Inclusion

  • ICF signature;
  • The subject must agree to follow the instructions and to perform study procedures and visits;
  • Male and female subjects between 18 and 65 years old;
  • Subjects who have scheduled a treatment or started the use of antibiotics over 24 hours ago:

Exclusion

  • Generalized infection or bacteremia;
  • Chronic gastrointestinal diseases (e.g., Crohn's Disease and Irritable Bowel Syndrome);
  • Documented chronic diarrhea;
  • Acute diarrhea episode within 24 hours prior to the start of antibiotic use. Use of tube feeding (nasogastric and nasoenteral);
  • Immunodeficiency (radiotherapy or chemotherapy);
  • Use of food with probiotic properties in the last 10 days;

Key Trial Info

Start Date :

February 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2012

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01463943

Start Date

February 1 2012

End Date

December 1 2012

Last Update

July 27 2015

Active Locations (17)

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Page 1 of 5 (17 locations)

1

UNICAMP

Campinas, Brazil

2

Unigastro

Campinas, Brazil

3

Hospital de Clínicas da Universidade Federal do Paraná

Curitiba, Brazil

4

Instituto de Prevenção ao Câncer do Ceará

Fortaleza, Brazil