Status:

COMPLETED

Effectiveness of Individualized Exercise Program, Combined With a Balanced Diet on the Evolution of Body Fat

Lead Sponsor:

Centre Hospitalier Universitaire de la Réunion

Conditions:

Obesity

Eligibility:

FEMALE

20-40 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the efficacy of 3 of physical exercise training programs, with a supplementation in fruits and vegetables, on body composition. 126 women will be randomized in...

Detailed Description

Background: in Reunion Island, in 2000 the REDIA study showed a prevalence of type 2 diabetes among 30-69 years old people above 17%, a prevalence of obesity among women of 20% and 10% for men. Accord...

Eligibility Criteria

Inclusion

  • women
  • 20-40 years old
  • 27 ≤ BMI ≤40 kg / m²
  • sedentary
  • considered clinically stable
  • able to rehabilitation training
  • having signed an informed consent
  • without professional activity

Exclusion

  • blood glucose ≥ 1.26 g / l
  • HbA1c ≥ 6.5%
  • severe hypertension (SBP ≥ 180 mmHg and / or DBP ≥ 110 mmHg)
  • hypertension (≥140/90 mmHg) untreated or treated by beta blocker or calcium blocker
  • absolute and relative contraindication to the maximal exercise test (ACC / AHA 2002) and / or physical training
  • inability to achieve the maximum exercise test and / or the metabolic exercise test by indirect calorimeter
  • uncompensated cardiovascular and / or respiratory disease revealed by exercise test
  • pacemaker or defibrillator
  • recent cardiovascular events (heart failure, treated by positive inotropic drugs, angioplasty within the last 10 days, cardiac surgery within the last 3 months, valvular disease requiring surgical correction, evolving myopericarditis, severe ventricular arrhythmias non stabilized under treatment)
  • known and documented myopathy
  • cancer
  • acute and chronic inflammatory disease
  • end stage renal disease
  • digestive system operation
  • treated by corticoids, thyroid hormone, antidepressant or neuroleptics
  • pregnancy
  • mental deficiency that prevents the understanding of informed consent and protocol
  • participation to another research protocol
  • attendance in the previous month to a program of rehabilitation training or a diet
  • associated evolutionary disease causing significant impairment of general condition.

Key Trial Info

Start Date :

November 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2012

Estimated Enrollment :

137 Patients enrolled

Trial Details

Trial ID

NCT01464073

Start Date

November 1 2011

End Date

September 1 2012

Last Update

July 29 2015

Active Locations (1)

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Centre Hospitalier Universitaire

Saint-Pierre, Île de La Réunion, France, 97448