Status:
COMPLETED
The Effect Of Glycemic Control On Malondialdehyde, Glutathione Peroxidase, Glutathione And Paraoxonase
Lead Sponsor:
Suleyman Demirel University
Conditions:
Type 2 Diabetes Mellitus
Chronic Periodontitis
Eligibility:
All Genders
Brief Summary
The aim of this study was to investigate the impact of glycemic control on clinical periodontal status, levels of malondialdehyde (MDA), glutathione peroxidase (GSH-Px), reduced glutathione (GSH) and ...
Detailed Description
Reactive oxygen species (ROS) are products of normal cellular metabolism and play beneficial role in physiological functions. Overproduction of ROS and/or deficiency of enzymatic or non-enzymatic anti...
Eligibility Criteria
Inclusion
- to present T2DM diagnosis by an endocrinologist for at least the past 5 years
- diagnosis of CP was based on the clinical and radiographic criteria proposed by the 1999 World Workshop for Classification of Periodontal Diseases and Conditions
Exclusion
- pregnancy
- lactation
- current smoking or smoking within the past 2 years, periodontal therapy in the previous 6 months
- antibiotic and/or antimicrobial therapies in the previous 3 months
- existence of serious diabetic complications or any pathology such as haemoglobinopathy which would affect haemoglobin profile
- diagnosis of another major medical pathology, middle or upper-level obesity according to WHO classification
- current anti-hyperlipidemic therapy
- non-T2DM patients with abnormal values of glucose and lipid metabolism parameters, major medical pathology and family history of DM
Key Trial Info
Start Date :
January 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2009
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT01467674
Start Date
January 1 2008
End Date
May 1 2009
Last Update
November 9 2011
Active Locations (1)
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1
Suleyman Demirel University
Isparta, Turkey (Türkiye), 32260