Status:
UNKNOWN
The Effect of Roux-en-Y Gastric Bypass on Mitochondrial Function in Type 2 Diabetes
Lead Sponsor:
Hvidovre University Hospital
Collaborating Sponsors:
University of Copenhagen
Conditions:
Type 2 Diabetes
Obesity
Eligibility:
All Genders
18-65 years
Brief Summary
Roux-en-Y gastric bypass (RYGB) surgery induces resolution of type 2 diabetes, often within days after surgery and before significant weight loss. The aim of this study is to investigate whether chang...
Detailed Description
Mitochondrial dysfunction has been linked to development of insulin resistance in the muscle and hence to the pathogenesis of type 2 diabetes. Mitochondrial function can be studied non-invasively by 3...
Eligibility Criteria
Inclusion
- Patients eligible for gastric bypass surgery or cholecystectomy
- Verified type 2 diabetes or normal glucose tolerance by OGTT
Exclusion
- Patients unable to fit the dimensions of the MRI-scanner
Key Trial Info
Start Date :
March 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2013
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01468116
Start Date
March 1 2011
End Date
December 1 2013
Last Update
November 9 2011
Active Locations (1)
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1
Hvidovre University Hospital
Copenhagen, Hvidovre, Denmark, DK-2650