Status:
COMPLETED
Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Hypoxemia
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
Alfentanil (Alf) is used in combination with Propofol (Pro) in fiber-bronchoscopy and in many other conscious sedation procedures. Alf and Pro have the characteristic of rapid anesthetic onset and qui...
Detailed Description
Alfentanil (Alf) is used in combination with Propofol (Pro) in fiber-bronchoscopy and in many other conscious sedation procedures. Alf and Pro have the characteristic of rapid anesthetic onset and qui...
Eligibility Criteria
Inclusion
- patients who required elective sedative bronchoscopy
Exclusion
- any physical, psychiatric, social problem that avoid from conscious level evaluation,
- hypersensitivity or allergy to Propofol, Alfentanil
- severe chronic obstructive pulmonary disease (forced expiratory volume in 1 s ,50% of predicted value, or requirement for oxygen therapy)
- unstable haemodynamic status (defined as a heart rate \< 60 or ≧ 120 bpm and/or
- a systolic blood pressure (SBP) \< 100 or ≧ 180 mmHg)
- predictable difficult upper airways (Mallampati classification score of IV)
- severe obstructive sleep apnea with apnea hypopnea index (AHI) \> 45
- Body mass index (BMI) more than 42 in male and 35 in female
- renal insufficiency
- liver cirrhosis
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
173 Patients enrolled
Trial Details
Trial ID
NCT01470170
Start Date
October 1 2010
End Date
December 1 2011
Last Update
August 13 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chang Gung Memorial Hospital
Taipei, Taiwan, 333