Status:
COMPLETED
Multiparametric MRI Study of Endogenous Analgesia and Prediction the Efficacy of Migraine Pharmacological Prevention
Lead Sponsor:
d_yarnitsky
Conditions:
Migraine
Eligibility:
FEMALE
18-50 years
Phase:
NA
Brief Summary
To delineate brain mechanisms that subserve EA in the healthy state and to identify alterations in mechanisms supporting EA in chronic pain and their therapeutic relevance. Individuals with migraine w...
Detailed Description
Pain is a uniquely individual experience that is powerfully shaped by the action of descending control mechanisms. These systems may play crucial roles in the moment-to-moment tuning of the sensitivit...
Eligibility Criteria
Inclusion
- patients diagnosed with migraine based on the International Headache Society (IHS) criteria 1 that have \>4 attacks/month, both with and without aura
Exclusion
- patients receiving any migraine preventive treatment during last 3 months or prior treatment with amytriptiline
- other chronic pain conditions
- psychiatric, other neurological diseases, language barrier or cognitive dysfunction
Key Trial Info
Start Date :
November 16 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 6 2017
Estimated Enrollment :
179 Patients enrolled
Trial Details
Trial ID
NCT01470352
Start Date
November 16 2011
End Date
November 6 2017
Last Update
March 27 2019
Active Locations (1)
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1
Rambam health care campus
Haifa, Israel