Status:
TERMINATED
Autologous Endometrial Coculture (AECCT)
Lead Sponsor:
Weill Medical College of Cornell University
Conditions:
Infertility
Eligibility:
FEMALE
18-38 years
Phase:
NA
Brief Summary
The purpose of this study is to determine if the use of Autologous Endometrial Coculture (AECC) in young in vitro fertilization (IVF) patients with poor ovarian reserve improves pregnancy outcome.
Detailed Description
Young women with poor ovarian reserve are commonly given a poor prognosis for IVF success. Standard culture media for fertilizing oocytes (unfertilized eggs) is commonly used in IVF which closely rese...
Eligibility Criteria
Inclusion
- Healthy women undergoing IVF at CRMI
- Age ≤ 38 years
- Poor ovarian reserve with antral follicle count less than 6 follicles, cycle day 2/3 FSH \> 12 ng/ml, AMH \< 0.5 ng/ml
Exclusion
- Healthy women undergoing IVF with male factor, severe endometriosis, or tubal factor infertility
- Donor patients
- Contraindications for the use of gonadotropins (i.e. pregnancy, lactation, undiagnosed vaginal bleeding or ovarian cysts)
- Recent or current medical conditions where the patient is not medically stable to undergo stimulation or egg retrieval, HIV infection, diabetes, cardiovascular disease, gastrointestinal, hepatic disease, renal or pulmonary disease.
- Any patient who is not a candidate for IVF
Key Trial Info
Start Date :
October 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2015
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01472861
Start Date
October 1 2009
End Date
June 1 2015
Last Update
June 12 2015
Active Locations (1)
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1
Center for Reproducutve Medicine; Weill Cornell Medical College
New York, New York, United States, 10021