Status:

COMPLETED

Analysis of Growth Factors in Patients Undergoing Lucentis or Avastin Injections for Diabetic Macular Edema and Exudative Macular Degeneration

Lead Sponsor:

Vitreo-Retinal Associates, Michigan

Collaborating Sponsors:

Van Andel Research Institute

Conditions:

Exudative Macular Degeneration

Diabetic Macular Edema

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

The purpose of this study is to measure biomarkers in the vitreous of patients undergoing Lucentis or avastin treatment.

Eligibility Criteria

Inclusion

  • Male or female age 18 to 85 with diabetes and hemoglobin A1C \</= 10, or exudative macular degeneration.
  • Diabetic macular edema with average retinal thickness central subfield \>/= 290um.

Exclusion

  • Macular atrophy/fibrosis.
  • Ocular anti-VEGF treatment within 3 months.
  • Treatment with topical or oral carbonic-anhydrase inhibitor within one month
  • Laser photocoagulation within 3 months (diabetic cohort)

Key Trial Info

Start Date :

November 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2014

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT01473251

Start Date

November 1 2011

End Date

April 1 2014

Last Update

December 17 2014

Active Locations (1)

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Vitreo-Retinal Associates

Grand Rapids, Michigan, United States, 49525