Status:
COMPLETED
RYGB and the Gastric Adipose Axis
Lead Sponsor:
Vanderbilt University
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Obesity
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to determine if interruption in gastric-adipose tissue axis signaling contributes to early improvements in oxidative stress, insulin sensitivity, and inflammation, and to ...
Eligibility Criteria
Inclusion
- PROTOCOL I
- Age 18-65 years
- BMI ≥ 35 kg/m\^2
- Scheduled for bariatric surgery
- Considering bariatric surgery
- Waiting for insurance approval for bariatric surgery
- Currently not considering bariatric surgery, but otherwise eligible
- Enrollment in medical weight loss program
Exclusion
- Smoking \>7 cigarettes per day
- Precious malabsorptive or restrictive intestinal surgery
- Pregnant or breastfeeding
- Recent history of neoplasia (5\<years ago)
- Malabsorptive syndromes
- Inflammatory intestinal disease
- Established organ disfunction
- Allergy to acetaminophen
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2015
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT01474785
Start Date
January 1 2012
End Date
July 1 2015
Last Update
May 21 2018
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 34232