Status:
TERMINATED
Step Down Colon Cancer Risk
Lead Sponsor:
Washington University School of Medicine
Conditions:
Adenomatous Polyps
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
Hypothesis 1: Exercise will decrease serum markers in a dose response manner. Hypothesis 2: Participants in the 60 minute intervention will have significantly higher physical activity levels than tho...
Detailed Description
Primary Aim: To conduct a dose response pilot trial of low (30 min/day) or high (60 min/day) dose exercise in men and women at increased risk of colon cancer. The major outcomes are changes in serum l...
Eligibility Criteria
Inclusion
- aged 50 to 80
- no personal cancer history
- found to have an adenomatous polyp upon colonoscopy at BJH/WUSM in the previous six months
- no contraindications to beginning an exercise program
- no previous diagnosis of familial polyposis syndromes
- no previous diagnosis of ulcerative colitis or Crohn's disease;
Exclusion
- Participants who are regular NSAID users will be excluded as this may interfere with the measurement of inflammatory marker outcomes. Regular use is defined as taking 80mg or more per day of aspirin, ibuprofen, naproxen or other NSAID 5 or more days of the week.
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2010
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT01476631
Start Date
November 1 2008
End Date
April 1 2010
Last Update
August 5 2013
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110