Status:
COMPLETED
Dietary Intervention and Intestinal Microbiota in Non-alcoholic Fatty Liver
Lead Sponsor:
University Hospital, Geneva
Conditions:
Obesity
Non-alcoholic Fatty Liver Disease (NAFLD)
Eligibility:
All Genders
18-60 years
Brief Summary
In patients with NAFLD/NASH, changes in liver lipid composition and function tests following a short dietary intervention are associated with changes in gut microbiota
Detailed Description
Study Hypothesis: In patients with NAFLD/NASH, changes in liver lipid composition and function tests following a short dietary intervention are associated with changes in gut microbiota Study period:...
Eligibility Criteria
Inclusion
- Obesity defined as BMI\>30 Abnormal liver function tests defined as ALT \> 1.5 times the upper limit of normal NAFLD present at liver biopsy Age \> 18 years, \< 60 years
Exclusion
- Inability or unwillingness to give consent Bulimia Other known cause of chronic liver disease, including hepatitis B or C, iron overload, Use of substances known to alter intestinal permeability, including alcohol and NSAIDs
Key Trial Info
Start Date :
July 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 15 2016
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01477307
Start Date
July 1 2013
End Date
September 15 2016
Last Update
October 26 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Geneva University Hospital
Geneva, Switzerland, 1211