Status:

COMPLETED

Study of Reduced Anti-coagulation/Anti-platelet Therapy in Patients With the HeartMate II Left Ventricular Assist System (LVAS) (TRACE)

Lead Sponsor:

Abbott Medical Devices

Collaborating Sponsors:

Thoratec Europe Ltd

Conditions:

Anticoagulation

Left Ventricular Assist Device

Eligibility:

All Genders

Brief Summary

The purpose of this observational study is to obtain multi-center data on HeartMate II (HMII) patients managed with reduced anticoagulation or anti-platelet regimes, and the incidence of thrombotic an...

Eligibility Criteria

Inclusion

  • HeartMate II Left Ventricular Assist Device (LVAD) patient
  • Patient has signed an informed consent for data collection.
  • Patient was discharged, or is being discharged, from the hospital after their initial LVAD implant surgery.
  • Patient:
  • at time of enrolling in study, is currently on, with the intention of being maintained on reduced anti-thrombotic therapy (RT) for chronic long-term management.
  • OR
  • \-- On or after January 1, 2011 patient was being maintained on, or had been initiated with the intention of being maintained on, reduced anti-thrombotic therapy (RT) for chronic long-term management; but where RT was subsequently discontinued due to an adverse event or transplant, explant, or death.

Exclusion

  • Patients under acute management of anti-thrombotic agents before a final decision on long term antithrombotic strategy.
  • Patients requiring a legal representative to sign consent form, rather than themselves.
  • Patient is being managed on other anti-thrombotic agents

Key Trial Info

Start Date :

November 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2015

Estimated Enrollment :

201 Patients enrolled

Trial Details

Trial ID

NCT01477528

Start Date

November 1 2011

End Date

August 1 2015

Last Update

June 24 2022

Active Locations (18)

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Page 1 of 5 (18 locations)

1

Sharp Memorial Hospital

San Diego, California, United States, 92123

2

University of Florida (Shands)

Gainesville, Florida, United States, 32610

3

Advocate Christ Hospital

Oak Lawn, Illinois, United States, 60453

4

Methodist Hospital of Indiana

Indianapolis, Indiana, United States, 46202