Status:
COMPLETED
Glucose Metabolism Effects of Vitamin D Supplementation in Prediabetes
Lead Sponsor:
University of Eastern Finland
Collaborating Sponsors:
Academy of Finland
Juho Vainio Foundation
Conditions:
Prediabetic State
Overweight
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Vitamin D deficiency is widespread throughout the world, and the deficiency has been associated with several chronic diseases, such as cardiovascular diseases and diabetes. In Nordic countries, like i...
Eligibility Criteria
Inclusion
- Age 60 years or older
- Serum calcidiol \<75 nmol/L
- Body mass index 25-35 kg/m2
- Impaired fasting glucose or impaired glucose tolerance (fasting glucose 5.6-7.0 mmol/L or 2h oral glucose tolerance test glucose 7.8-11.0 mmol/L)
Exclusion
- Any chronic disease and condition, which may hamper to follow the intervention protocol (such as alcohol abuse)
- Any chronic disease or therapy which may mask or interact with the investigated effects (such as diabetes or systemic corticosteroid therapy)
- Any disease or state that raises a vitamin D related safety concern (such as chronic liver, thyroid or kidney disease, hypercalcemia, sarcoidosis or other granulomatous diseases such as active chronic tuberculosis or Wegener's granulomatosis)
- Use of supplements yielding vitamin D over 20 µg/d and unwillingness to discontinue the use.
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
73 Patients enrolled
Trial Details
Trial ID
NCT01479933
Start Date
September 1 2011
End Date
May 1 2012
Last Update
March 5 2013
Active Locations (1)
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1
University of Eastern Finland, Kuopio Campus
Kuopio, Kuopio, Finland, 70211