Status:

COMPLETED

Evaluation of Posterior Capsule Opacification in Eyes With Diabetes Mellitus

Lead Sponsor:

Iladevi Cataract and IOL Research Center

Conditions:

Development of Posterior Capsule Opacification

Eligibility:

All Genders

50-75 years

Brief Summary

To compare the development of posterior capsule opacification (PCO) between eyes with and without a history of diabetes mellitus (DM) after single-piece hydrophobic acrylic intraocular lens (IOL) impl...

Detailed Description

There is a paucity of available literature that prospectively evaluates the development of PCO with the single-piece hydrophobic acrylic IOL implantation in diabetic versus non-diabetic eyes on a long...

Eligibility Criteria

Inclusion

  • Diabetes mellitus was defined as glycosylated haemoglobin (Hb A1c ) levels of 6% or more ,
  • use of diabetic medication (oral hypoglycemic agents, insulin injection or diet restriction), or a physician's diagnosis of diabetes.
  • Patients with uncomplicated age-related cataract who were otherwise healthy constituted the controls (n=75 eyes).

Exclusion

  • patients with glaucoma,
  • high myopia (axial length \> 27.0 mm),
  • pseudoexfoliation,
  • traumatic cataract,
  • subluxated cataract,
  • previous ocular surgeries,
  • allergy to dilating drops.

Key Trial Info

Start Date :

June 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2010

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT01480934

Start Date

June 1 2005

End Date

June 1 2010

Last Update

November 29 2011

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