Status:

COMPLETED

Performance Study of New Media for Vitrification of Human Oocytes

Lead Sponsor:

Vitrolife

Conditions:

Infertility

Eligibility:

FEMALE

18-37 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate safety and performance of Vitrolife´s new oocyte vitrification/warming media and the vitrification device Rapid-i™, when using vitrification as a cryopreservat...

Detailed Description

A multi-center prospective sibling oocyte vitrification trial where, in the first phase, half of the patients' oocytes will be vitrified and warmed (experimental group). The remaining oocytes will not...

Eligibility Criteria

Inclusion

  • Couple agreed to participate in study and has signed the Informed Consent Document before any study-related activities
  • Patient age (female): 18-37 years (including oocyte donors)
  • BMI 18-27 kg/m2 (female)
  • 2 ovaries, normal uterine cavity (female)
  • Day 3 FSH ≤ 10mIU, E2 \<80 pg/mL and an AFC ≥12 (both ovaries, 3 mm or greater) (female)
  • AMH \>1 (female)
  • Ejaculatory sperm (male)
  • ICSI fertilization
  • Long standard stimulation protocol
  • English speaking

Exclusion

  • Previous participation in the study
  • ≥2 previous failed IVF cycles
  • Endometrioma
  • Presence of a hydrosalpinx
  • History of recurrent miscarriage (defined as ≥2 clinical recognized SABs)
  • Not willing to have ICSI performed
  • Cycle length \>6 weeks \[a diagnosis of PCOS will not exclude from the study unless typical cycle length is greater than 6 weeks; this criteria would exclude hypothalamic-hypogonadotropic patients\]

Key Trial Info

Start Date :

January 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2012

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT01481571

Start Date

January 1 2012

End Date

September 1 2012

Last Update

March 24 2014

Active Locations (2)

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Page 1 of 1 (2 locations)

1

The DFW Fertility Associates, Reproductive Endocrinology and Infertility, Dallas Fertility Centre

Dallas, Texas, United States, 75231

2

Frisco IVF

Frisco, Texas, United States, 75034