Status:

UNKNOWN

Epidemiological, Clinical and Etiological Features of SUSAC's Syndrome

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

SUSAC's Syndrome

Encephalopathy

Eligibility:

All Genders

18+ years

Brief Summary

SUSAC's Syndrome (SS) is characterized by the clinical triad of encephalopathy, hearing loss, and retinal artery branch occlusions. Since the first description of SS in 1979, hundreds of patients with...

Detailed Description

SUSAC's Syndrome (SS) is characterized by the clinical triad of encephalopathy, hearing loss, and retinal artery branch occlusions. Since the first description of SS in 1979, hundreds of patients with...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Age older than 18
  • Two clinical features of the triad present: encephalopathy, sensorineural hearing loss assessed by audiogram, retinal artery occlusion assessed by fundoscopy or fluorescein retinal angiography.
  • Written informed consent provided. In case of subjects unable to give a written informed consent because of encephalopathy associated with the disease, a written statement of non-opposition should be signed by a relative. This non-opposition statement should be then confirmed by the subject as soon as possible.
  • Realization of a medical examination beforehand
  • EXCLUSION CRITERIA:
  • Alternative diagnosis: multiple sclerosis, mitochondriopathy, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), primary brain tumor, Lyme disease.
  • In case of associated disease (autoimmune disease, tumor, metabolical disease,…), inclusion will need further analysis by the expert comity.
  • Not membership in a national insurance scheme

Exclusion

    Key Trial Info

    Start Date :

    November 1 2011

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    May 1 2021

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT01481662

    Start Date

    November 1 2011

    End Date

    May 1 2021

    Last Update

    December 21 2017

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Hospital BICHAT

    Paris, France, 75018