Status:

COMPLETED

Delayed Postconditioning

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Myocardial Reperfusion Injury

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The investigators previously reported that angioplasty postconditioning reduces infarct size (cardiac enzyme release) in STEMI patients with a fully occluded coronary artery at hospital admission. Ani...

Eligibility Criteria

Inclusion

  • Patient \> 18 years old
  • Male or female
  • Presenting first myocardial infarction, with the beginning of pains \< 12 hours,
  • Requiring a revascularisation by primary angioplasty or " rescue " (after failure of thrombolysis) on LAD or RCA (not Circumflex coronary artery).
  • TIMI flow grade at admission of 2 or 3
  • LV angiography (RAO30°) before angioplasty.

Exclusion

  • Cardiac arrest before the angioplasty
  • Cardiogenic shock
  • Occlusion of the artery circumflex responsible for the infarction
  • Visible collaterals to the area at risk
  • Magnetic resonance imaging: contra indication

Key Trial Info

Start Date :

July 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2012

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT01483755

Start Date

July 1 2009

End Date

June 1 2012

Last Update

December 19 2025

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Service de Cardiologie, CHU d'Angers

Angers, France, 49933

2

Service d'explorations Fonctionnelles Cardiovasculaires, Hôpital Cardiologique Louis Pradel

Bron, France, 69677

3

Service de Cardiologie, Hôpital Arnaud de Villeneuve

Montpellier, France, 34295

4

Service de Cardiologie, Hôpital Emile Müller

Mulhouse, France, 68051