Status:

COMPLETED

Selected Site Pacing to Avoid Phrenic Nerve Stimulation in Cardiac Resynchronization Patients With Quadripolar Left Ventricular Leads

Lead Sponsor:

Abbott Medical Devices

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Brief Summary

Cardiac resynchronization (CRT) therapy is well established for treatment of patients with severe heartfailure, reduced left ventricular (LV) function and ventricular dyssynchrony. Roughly 1/3 of CRT ...

Detailed Description

Definition of an acceptable lead vector: Any LV pacing vector that complies in both tested body positions (left lateral position and sitting) with both criteria: 1. Phrenic nerve stimulation threshol...

Eligibility Criteria

Inclusion

  • Indication for implantation of a CRT-D
  • Age \>= 18 years
  • Written informed consent

Exclusion

  • Already implanted LV or coronary sinus lead
  • Previous unsuccessful LV lead implant attempt
  • Patient is eligible for heart transplantation
  • Comorbidities that results in life expectancy of less than 12 months
  • Known pregnancy
  • Inability to provide written patient informed consent
  • Participation to another study with active treatment arm (i.e. randomized studies etc...)
  • Patient is not willing or is not able to visit the study center for the study assessments within the first 3 months after implant
  • Patient is not able to understand or answer the quality of life questionaire

Key Trial Info

Start Date :

November 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2014

Estimated Enrollment :

337 Patients enrolled

Trial Details

Trial ID

NCT01484613

Start Date

November 1 2011

End Date

June 1 2014

Last Update

February 4 2019

Active Locations (16)

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Page 1 of 4 (16 locations)

1

Klinikum Coburg GmbH

Coburg, Germany, 96450

2

Evangelisches Krankenhaus Kalk

Cologne, Germany, 51103

3

Krankenhaus Mörsenbroich-Rath GmbH

Düsseldorf, Germany, 40472

4

Klinikum Esslingen

Esslingen am Neckar, Germany, 73730