Status:

UNKNOWN

Bevacizumab Versus Ranibizumab for the Treatment of Diabetic Macular Edema

Lead Sponsor:

University of Sao Paulo

Collaborating Sponsors:

Fundação de Amparo à Pesquisa do Estado de São Paulo

Conditions:

Diabetic Retinopathy

Macular Edema

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to compare the morphological and visual acuity outcomes associated with 1.5 mg bevacizumab versus 0.5 ranibizumab intravitreal injections for treatment of diabetic macular...

Eligibility Criteria

Inclusion

  • Center-involving Diabetic macular edema unresponsive to LASER therapy performed at least 3 moths prior to inclusion;
  • Best corrected visual acuity equal or worse than 20/40 and better than 20/800;
  • Central subfield macular thickness greater than 300 µm

Exclusion

  • Aphakia
  • High-risk proliferative diabetic retinopathy
  • Previous treatment for DME in the past three months

Key Trial Info

Start Date :

April 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2012

Estimated Enrollment :

53 Patients enrolled

Trial Details

Trial ID

NCT01487629

Start Date

April 1 2010

End Date

September 1 2012

Last Update

December 13 2011

Active Locations (1)

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1

Clinics Hospital of Ribeirão Preto, School of Medicine of Ribeirão Preto, USP

Ribeirão Preto, São Paulo, Brazil, 14048-900