Status:

COMPLETED

Biomarkers in Tissue Samples From Patients With Recurrent or Metastatic Head and Neck Cancer Treated on ECOG-E1395 and ECOG-E3301

Lead Sponsor:

Eastern Cooperative Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Head and Neck Cancer

Eligibility:

All Genders

18-120 years

Brief Summary

RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors predict how well patients will respond to treatment. PURPOSE: This research study is studying biomar...

Detailed Description

OBJECTIVES: * To investigate the association between biomarkers (HPV tumor status and ERCC1 expression) and clinical outcomes in a population of patients with recurrent or metastatic head and neck ca...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Tissue specimens from patients with recurrent or metastatic head and neck cancer treated on ECOG-E1395 and ECOG-E3301
  • Stage III, IV, or recurrent disease
  • Squamous cell disease
  • Any of the following diagnoses:
  • Lip and oral cavity
  • Oropharynx
  • Hypopharynx
  • Larynx
  • Paranasal sinus and nasal cavity
  • Squamous neck cancer
  • Salivary gland
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Exclusion

    Key Trial Info

    Start Date :

    December 22 2011

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    January 22 2012

    Estimated Enrollment :

    155 Patients enrolled

    Trial Details

    Trial ID

    NCT01487733

    Start Date

    December 22 2011

    End Date

    January 22 2012

    Last Update

    May 17 2017

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