Status:
COMPLETED
TREM-1 Gene Polymorphisms
Lead Sponsor:
Chinese PLA General Hospital
Conditions:
Sepsis
Eligibility:
All Genders
18+ years
Brief Summary
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a cell surface receptor expressed on neutrophils and monocytes. TREM-1 acts to amplify inflammation and serves as a critical mediator of in...
Eligibility Criteria
Inclusion
- Sepsis met the criteria recommended by 1991 ACCP/SCCM Joint Meeting and by the diagnostic criteria developed at the 2001 International Sepsis Definition Conference.
Exclusion
- (1) younger than 18 years of age; (2) acquired immunodeficiency syndrome; (3) reduced polymorphonuclear granulocyte counts (\< 500 μL-1); (4) died within 24h after admission into the ICU, or refused to participate in the study, or declined treatment during the period of observation.
Key Trial Info
Start Date :
May 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT01490424
Start Date
May 1 2010
End Date
October 1 2011
Last Update
December 13 2011
Active Locations (1)
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1
Chinese PLA General Hospital
Beijing, Beijing Municipality, China, 100853