Status:
COMPLETED
Bariatric Surgery, Arterial Stiffness and Target Organ Damage Study (BASTOD)
Lead Sponsor:
University Hospital, Montpellier
Conditions:
Hypertension
Obesity
Eligibility:
All Genders
18-60 years
Brief Summary
Introduction: Obesity is a major public health problem, associated with many morbidities, including metabolic and cardiovascular disease (CVD). High blood pressure (hypertension) is the most common c...
Detailed Description
Objective: The study aims to (a) estimate the effects of bariatric surgery on the function of large arteries (determined non-invasively by measurement of PWV, pressure central reflection wavelength) ...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- BMI \> 40 kg/m2 or BMI 35-40 with major comorbidities
- Age between 18-60 years
- Obesity evolving for more than 5 years
- Failure of medical treatment
- Elimination of hormonal causes
- Exclusion criteria:
- Uncontrolled hypertension (SBP \> 160 mmHg and DBP\> 100 mmHg).
- History of cardiovascular disease or signs of clinical atheroma: stroke, myocardial infarction and coronary heart disease (angina), peripheral arterial disease (no pulse, claudication), aortic aneurysm (anterior abdominal palpation or imaging ), carotid bruit
- Plasma creatinine \> 130 micromol/L and/or proteinuria \> 300 mg/24 h and/or dipstick hematuria.
Exclusion
Key Trial Info
Start Date :
December 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2016
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01494168
Start Date
December 1 2011
End Date
March 1 2016
Last Update
December 1 2016
Active Locations (1)
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1
University Hospital
Montpellier, France, 34925