Status:
COMPLETED
Validation of the Bispectral Index Monitor During Living Donor Liver Transplantation
Lead Sponsor:
Mansoura University
Conditions:
Liver Cirrhosis
Eligibility:
All Genders
20-50 years
Brief Summary
Bispectral index (BIS) monitoring during living donor liver transplantation (LDLT) may be influenced with several factors rather than the depth of anesthesia such as bradycardia, hypotension, hypother...
Detailed Description
Forty two American Society of Anesthesiologists physical class III-IV patients aged 20-50 years with severe liver dysfunction (Child-Pugh Class C) due to liver cirrhosis undergoing living donor liver ...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists physical class III-IV
- aged 20-50 years
- severe liver dysfunction
- Child-Pugh Class C
- liver cirrhosis
Exclusion
- preexisting significant neuropsychiatric
- cardiac diseases
- pulmonary diseases
- renal diseases
- neuromuscular diseases
- electrolyte disorders
- body mass index greater than 35 kg/m2
- pregnancy
- use of antipsychotics
- use of antidepressants
- alcohol abuse
- drug abuse
- previous transplantation
- those with hepatic encephalopathy
- recent cognitive dysfunction during the past three months
- fulminant hepatic failure
- hepato-pulmonary syndrome
- pulmonary hypertension
Key Trial Info
Start Date :
June 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2011
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT01494220
Start Date
June 1 2007
End Date
February 1 2011
Last Update
April 4 2012
Active Locations (1)
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1
College of Medicine, Mansoura University
Al Mansurah, DK, Egypt, 050