Status:
COMPLETED
Holmium Laser Enucleation of Prostate(HOLEP) vs Greenlight(XPS) Laser Photoselective Vapo-Enucleation of Prostate(PVEP)
Lead Sponsor:
Royal Victoria Hospital, Canada
Collaborating Sponsors:
McGill University
Conditions:
Benign Prostate Hyperplasia
Eligibility:
MALE
Phase:
PHASE4
Brief Summary
The investigators are now proposing to compare two laser techniques for treating Benign prostate hyperplasia (BPH); Holmium Laser Enucleation of the Prostate (HOLEP) versus (greenlight) XPS which is a...
Detailed Description
Patients with lower urinary tract symptoms (LUTS) secondary to bladder outlet obstruction from BPH seen through the outpatient clinic in the urology department will be assessed to see if the patient s...
Eligibility Criteria
Inclusion
- Ability to give informed consent.
- Lower urinary symptoms (LUTS) secondary to bladder outlet obstruction from BPH.
- Failed medical treatment of BPH.
- International prostate symptom scores (IPSS) \> 15.
- Peak urinary flow rate (Qmax) \< 15 ml/sec.
- Preoperative TRUS (transrectal ultrasound) size of the gland (from 40 to 150 cc).
- Patients in retention secondary to BPH (with cystometrogram (CMG) confirming adequate detrusor pressure if the bladder capacity at time of catheterization is in excess of 1000 ml).
Exclusion
- Inability to give informed consent.
- Patient who have a neurological disorder which might affect bladder function as cerebrovascular stroke, Parkinson disease.
- Active urinary tract infection.
- Presence of active bladder cancer (within the last 2 years).
- Known cancer prostate patients will be excluded preoperatively on the basis of digital rectal examination, prostate specific antigen level, and TRUS imaging followed by prostate biopsies if necessary.
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2014
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT01494337
Start Date
January 1 2012
End Date
April 1 2014
Last Update
August 26 2014
Active Locations (1)
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1
Royal victoria hospital
Montreal, Quebec, Canada, H3A 1A1