Status:
UNKNOWN
The Changes of CD4+T Lymphocyte Subsets in Septic Patients
Lead Sponsor:
Chinese PLA General Hospital
Conditions:
Sepsis
SIRS(Systemic Inflammatory Response Syndrome)
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to explore the value of CD4+T lymphocyte subsets in cell immunity in the patients with sepsis.There are immunoparalysis in septic patients,the important player is the chan...
Eligibility Criteria
Inclusion
- Male and female aged 18 years old and over;
- Fulfilled at least two criteria of systemic inflammatory response syndrome (a) core temperature higher than 38 °C or lower than 36 °C (b)respiratory rate above 20/min, or PCO2 below 32 mmHg (c) pulse rate above 90/min, and (d) white blood cell count greater than 12,000/μl or lower than \< 4,000/μl or less than 10% of bands.
- Clinically suspected infection;
Exclusion
- were under 18 years of age;
- were refused by the patients or his/her familiality;
- were suffering from acquired immunodeficiency syndrome,virlhepatitis,autoimmune diseases and hematology;
- use medicine which can affect immune system,such as Glucocorticoid and Immunosuppressant
- died within 24h after being taken into the ICU, or refused to get involved in the study, or gave up treatment during the period of observation
Key Trial Info
Start Date :
August 1 2011
Trial Type :
OBSERVATIONAL
End Date :
March 1 2012
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01494389
Start Date
August 1 2011
End Date
March 1 2012
Last Update
December 19 2011
Active Locations (1)
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1
Chinese PLA General Hospital
Beijing, Beijing Municipality, China, 100853