Status:
UNKNOWN
The Effect of Two Airway Interventions, During One Lung Ventilation, on Blood Oxygen Content
Lead Sponsor:
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions:
Thoracic, Diseases
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Patients requiring one lung ventilation (OLV) for open thoracic surgery will be ventilated (breathing performed by a breathing machine) during anesthesia using a lung protective ventilation strategy (...
Detailed Description
Patients requiring one lung ventilation (OLV) for open thoracic surgery will be ventilated intra-operatively using a lung protective ventilation strategy (small tidal volumes {Vts} at 6ml/kg Ideal Bod...
Eligibility Criteria
Inclusion
- Age 18 or older
- Competent to give consent to enroll in study
- Booked for scheduled open thoracotomy which involves wedge resection, lobectomy or pneumonectomy requiring OLV
- American Society of Anesthesia physical status score (ASA) 1-4
Exclusion
- Unable to give consent
- Pregnant women
- Inability to insert an arterial line
- Presence of other significant pulmonary impairment (PaO2 on room air \<50mmHg, PaCO2 \>50mmHg or known pulmonary hypertension (mean PAP\>25mmHg)
- Presence of significant cardiovascular disease
- Altered liver function (Child Pugh scale ≥B)
- Patients with bullous lung disease. -
Key Trial Info
Start Date :
October 17 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2017
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01495936
Start Date
October 17 2011
End Date
December 1 2017
Last Update
November 6 2017
Active Locations (1)
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1
Victoria Hospital
London, Ontario, Canada, N6A 5W9