Status:
COMPLETED
The Cortisol Levels During Cardiac Surgery. The Comparison Between Etomidate and Thiopentone
Lead Sponsor:
Mahidol University
Conditions:
Coronary Artery Disease
Valvular Heart Disease
Eligibility:
All Genders
60-85 years
Phase:
PHASE4
Brief Summary
During induction for cardiac surgery, patient hemodynamic stability is achieved by using anesthetic drugs which least affects hemodynamics such as benzodiazepines, etomidate. Etomidate although has be...
Detailed Description
Ninety-two cardiac patients who undergoing cardiopulmonary bypass graft (CABG) or valve surgery will be enrolled in this study. They will be randomized into two groups (thiopentone and etomidate group...
Eligibility Criteria
Inclusion
- 60 year or older cardiac patient undergoing cardiac surgery (CABG or valve surgery) with the use of cardiopulmonary bypass -
Exclusion
- Redo or emergency operation
- complex and prolong operation
- history of adrenal insufficiency or steroid use
- already has inotropic drugs to support hemodynamics
- creatinine \> 2.0 mg/dl
Key Trial Info
Start Date :
December 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT01495949
Start Date
December 1 2011
End Date
December 1 2013
Last Update
May 23 2014
Active Locations (1)
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1
Siriraj Hospital Mahidol University
Bangkok, Thailand, 10700