Status:

COMPLETED

Multimodality Neuromonitoring in XLIF

Lead Sponsor:

NuVasive

Conditions:

Degeneration of Lumbar Intervertebral Disc

Eligibility:

All Genders

18+ years

Brief Summary

This is a prospective, non-randomized multi-center study to evaluate intraoperative neuromonitoring results in subjects who undergo eXtreme Lateral Interbody Fusion (XLIF) surgery at any number of lev...

Detailed Description

Subjects will present with degenerative conditions in the lumbar spine that are amenable to surgical treatment and will be screened prior to study enrollment. Subjects will undergo neuromonitoring dur...

Eligibility Criteria

Inclusion

  • Persistent back and/or leg pain unresponsive to conservative treatment for at least six (6) months, unless surgical treatment is clinically indicated earlier
  • Indicated for extreme lateral interbody fusion at any number of levels inclusive of L4-5
  • At least 18 years of age at the date of written informed consent
  • Able to undergo surgery based on physical exam, medical history and surgeon judgment
  • Willing and able to return for post-treatment exams according to the follow-up called for in the protocol
  • Signed and dated informed consent form

Exclusion

  • Patient has a mental or physical condition that would limit the ability to comply with study requirements
  • Patient is a prisoner
  • Patient is involved in active litigation relating to the spine (worker's compensation claim is allowed if it is not contested)
  • Patient has an underlying neurological disease or neurological deficit that is not associated with the condition for which he/she is seeking surgical intervention (e.g., diabetic peripheral neuropathy)
  • Patient is participating in another clinical study that would confound study data

Key Trial Info

Start Date :

October 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2014

Estimated Enrollment :

323 Patients enrolled

Trial Details

Trial ID

NCT01499680

Start Date

October 1 2011

End Date

June 1 2014

Last Update

December 24 2025

Active Locations (20)

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Page 1 of 5 (20 locations)

1

Shiley Center for Orthopaedic Research

La Jolla, California, United States, 92037

2

UC Irvine Medical Center

Orange, California, United States, 92868

3

Durango Orthopaedics

Durango, Colorado, United States, 81301

4

USF Neurology and Neurosurgery

Tampa, Florida, United States, 33606