Status:

COMPLETED

Quality Study of Anesthetic Technique on Breast Cancer Surgery

Lead Sponsor:

Nai Liang Li

Conditions:

Postoperative Pain

Quality of Recovery

Eligibility:

FEMALE

18-70 years

Phase:

PHASE4

Brief Summary

Previous studies have shown that paravertebral block (PVB) has the potential to reduce pain and side effects after breast surgery when used in addition to general anesthesia or sedation.The investigat...

Eligibility Criteria

Inclusion

  • Patient has a physical status between ASA I and III
  • Female
  • 18 - 70 years of age
  • Patients able to read a newspaper in Chinese.
  • Elective unilateral wide excision/simple mastectomy and SLNB/ALND
  • Patient has signed an informed consent
  • Without contraindication of GA or PVB
  • Body mass index (BMI) less than 24 kg/m2

Exclusion

  • ASA \> III
  • inability to provide informed consent
  • Bleeding disorders
  • Contraindications to nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Allergy to amide-type local anesthetics or NSAIDs
  • Infection at the thoracic paravertebral injection site
  • Pregnancy or breast-feeding
  • Severe spine or chest wall deformity
  • body mass index equal to or more than 24 kg/m2
  • patients with major psychosis or drug and alcohol abuse
  • patients with a history of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease
  • Patients with significant visual impairment or other physical disability that precludes complete cooperation

Key Trial Info

Start Date :

January 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2013

Estimated Enrollment :

101 Patients enrolled

Trial Details

Trial ID

NCT01499836

Start Date

January 1 2012

End Date

June 1 2013

Last Update

January 16 2014

Active Locations (1)

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1

Koo Foundation Sun Yat-Sen Cancer Center

Taipei, Taiwan, Taiwan, 11259