Status:
COMPLETED
Hypothermic Perfusion During Hemihepatectomy
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions:
Hepatic Ischemia-reperfusion Injury
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Rationale Currently, hepatic resection is often the only curative treatment for primary or secondary hepatic malignancies and is also frequently performed in patients with benign liver tumors to prev...
Eligibility Criteria
Inclusion
- Patients scheduled for right hemihepatectomy under vascular inflow occlusion for a malignant or benign hepatic tumor
- Diagnostic exclusion of hepatic co-morbidity, that is:
- Cirrhosis,
- Severe steatosis (≥ 30%),
- Cholestasis, and
- Hepatitis B/C infection
- Age ≥ 18 years
- Signed informed consent obtained prior to any study-specific procedure
- ASA classification I-III
Exclusion
- Patients diagnosed with any of the hepatic co-morbidities listed under point 2 of the inclusion criteria
- Age \< 18 years
- BMI \> 35 kg/m2
- ASA classification IV/V
- Patient is scheduled for a combined surgical procedure (e.g., bile duct resection, gastrointestinal procedures)
- Patient underwent liver resection ≤ 1 year prior to scheduled surgery
- Emergency operations
- Pregnancy or breast feeding
Key Trial Info
Start Date :
February 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT01499979
Start Date
February 1 2012
End Date
August 1 2015
Last Update
January 26 2016
Active Locations (1)
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1
Academic Medical Center (AMC)
Amsterdam, North Holland, Netherlands, 1105 AZ