Status:
UNKNOWN
The Impact of Continuous Renal Replacement Therapy on the Outcomes of Burn Patients With Early Phase of Sepsis
Lead Sponsor:
Southwest Hospital, China
Conditions:
Burns
Sepsis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to determine if early application of CRRT will result in an improvement of clinical outcomes of burn patients during the early phase of sepsis
Detailed Description
The impact of Continuous Renal Replacement Therapy (CRRT) on the outcomes of patients with sepsis is controversial, and there is no consensus for the timing and dose of CRRT may improve the outcomes. ...
Eligibility Criteria
Inclusion
- patients with documented sepsis
- clinically identified focus of infection associated with at least 2 SIRS -criteria and one or more sepsis-induced organ failures within the 24 hours -prior to inclusion
- age 18 to 70 years
- severe burned patients with 50% \< TBSA \< 85%
Exclusion
- cirrhosis child class C
- too high APACHE II \& SOFA score at admission
- age over 70 years
- were presence of a malignant tumor, chronic renal insufficiency (serum creatinine \> 133 µmol/L), moribund state, receiving immunosuppressive therapy or receiving any kind of renal replacement therapy before randomization
Key Trial Info
Start Date :
December 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01501097
Start Date
December 1 2011
Last Update
December 30 2011
Active Locations (1)
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1
Southwest Hospital
Chongqing, Chongqing Municipality, China, 400038