Status:
COMPLETED
Effect of Sodium Lauryl Sulfate on Recurrent Aphthous Stomatitis
Lead Sponsor:
Yonsei University
Conditions:
Recurrent Aphthous Stomatitis
Eligibility:
All Genders
Phase:
NA
Brief Summary
Sodium lauryl sulfate (SLS) is an anionic detergent that has been used as the major or sole surfactant in most dentifrices. But it is known to local irritating factor to oral mucosa and skin and resul...
Eligibility Criteria
Inclusion
- The volunteers had a history of regularly recurring oral ulcerations of at least 6 months duration, with more than one episode per month
Exclusion
- already using an SLS-free dentifrice
- taking medications affecting oral ulcers (e.g., corticosteroids)
- having chronic oral mucosal disease (ex, lichen planus, pemphigus vulgaris, pemphigoid, and etc.)
- having allergies to food or medications
- being pregnant
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01501409
Start Date
January 1 2010
End Date
December 1 2010
Last Update
December 29 2011
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