Status:
COMPLETED
The Placebo Effect May Involve Modulating Drug Bioavailability
Lead Sponsor:
King Faisal Specialist Hospital & Research Center
Conditions:
Placebo Effect
Drug Half Life
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The total effect of a medication is the sum of its drug effect, placebo effect (meaning response of placebo), and their interaction. Current interpretation of clinical trials (the gold standard of evi...
Detailed Description
The total effect of a medication is the sum of its drug effect, placebo effect (meaning response of placebo), and their interaction. Current interpretation of clinical trials (the gold standard of evi...
Eligibility Criteria
Inclusion
- Having no evidence of clinically important deviation from normal health as indicated by medical history, vital signs, and clinical laboratory tests.
- Acceptance to abstain from taking any medication other than birth control pills (including over-the-counter drugs) for at least 1 week prior to, and during the study; and from smoking and taking alcohol or caffeine or related xanthenes-containing beverages or food for 48 hours before and throughout each study period.
- Having good peripheral venous access.
- For the caffeine study, habitual daily caffeine intake should be 100-300 mg.
Exclusion
- Women should be non-pregnant and non-lactating. For menstruating women, the study will be conducted 5 to 19 days after the last menstrual period and a urine pregnancy test will be performed.
- Should not have history of hypersensitivity to the drug to be tested or to its related compounds.
- Body Mass Index (BMI) should be less than 35 kg/m2.
Key Trial Info
Start Date :
February 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
162 Patients enrolled
Trial Details
Trial ID
NCT01501747
Start Date
February 1 2012
End Date
February 1 2013
Last Update
April 9 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
King Faisal Specialist Hospital & Research Center
Riyadh, Saudi Arabia, 11211