Status:

UNKNOWN

Evaluation of Generalization Paradigm Patterns Among Different Psychiatric Disorders

Lead Sponsor:

Shalvata Mental Health Center

Collaborating Sponsors:

Weizmann Institute of Science

Conditions:

MDD

Bipolar Disorder

Eligibility:

All Genders

20-65 years

Brief Summary

Learning includes the ability to generalize to new situations and respond to similar, yet not identical stimuli. In previous work, focused on stimulus generalization in healthy volunteers, tones that ...

Eligibility Criteria

Inclusion

  • Men and women 20-65 years of age.
  • Primary DSM-IV diagnosis of Schizophrenia, Schizoaffective, Bipolar (1 or 2) , Major depressive Disorder , Generalized anxiety disorder, panic disorder, post traumatic stress disorder based on SCID and confirmed by a senior psychiatrist, Or subjects without axis I or II diagnosis (control group).
  • Capable and willing to provide informed consent. In any case when there is doubt about the patients' capacity to sign an informed consent, an independent doctor will assess the patient capacities to make treatment decisions with the clinical tool MacCAT-T.
  • Able to adhere to the evaluation schedule.
  • Able to read, hear, write and speak Hebrew.
  • Has signed a written informed consent to participate in the study.

Exclusion

  • Patients with acute, unstable, significant, or untreated medical illness besides schizophrenia, anxiety disorder or affective disorder, including alcohol and drug dependence.
  • Subjects with significant cognitive impairment including dementia, history of head injury, mental retardation, or any other cause to "organic" cognitive impairment.
  • Current suicidal ideation or history of a suicide attempt in the past six month
  • Subjects who were under compulsory hospitalization.
  • Subjects with any other dominant axis I or II diagnosis mainly anxiety disorders, which might interfere with the evaluation of the above disorders.

Key Trial Info

Start Date :

March 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2013

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT01501812

Start Date

March 1 2011

End Date

June 1 2013

Last Update

December 29 2011

Active Locations (1)

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1

Shalvat Mental Health Center

Hod HaSharon, Israel