Status:

UNKNOWN

Biomarkers in Exhaled Breath Condensates of Septic Patients to Predict Development of Multi-organ Dysfunction Syndrome

Lead Sponsor:

National Taiwan University Hospital

Collaborating Sponsors:

National Science and Technology Council, Taiwan

Conditions:

Sepsis

Eligibility:

All Genders

20+ years

Brief Summary

In this proposal, the investigators wish to investigate, identify and validate potential biomarkers in collected exhaled breath condensates (EBC) from patients with sepsis.

Detailed Description

In this proposed project, we will focus on the identification of potential biomarkers in EBC with ability to predict development of multi-organ failure. Currently, no tools could be used to evaluate t...

Eligibility Criteria

Inclusion

  • above 20 years old
  • admitted to ICU with the diagnosis of sepsis and treated with mechanical ventilation via an endotracheal tube

Exclusion

  • pregnant
  • active malignancy
  • in an immunosuppressed status such as HIV disease, neutropenia, being treated with immunosuppressive agents
  • expected to have an unavoidable very short life expectancy after admission, i.e., \< 3 days

Key Trial Info

Start Date :

August 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT01503684

Start Date

August 1 2011

Last Update

January 4 2012

Active Locations (1)

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1

National Taiwan University Hospital

Taipei, Taiwan, 100