Status:
COMPLETED
Effect of the Adjunctive IVB Before PRP
Lead Sponsor:
Kyungpook National University Hospital
Conditions:
Diabetic Retinopathy
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
This study is to investigate the effect of adjunctive intravitreal bevacizumab (IVB) before panretinal photocoagulation (PRP) compared with only PRP on central macular thickness and retinal nerve fibe...
Detailed Description
This prospective randomized study included 30 patients (60 eyes) with severe nonproliferative diabetic retinopathy or non-high-risk proliferative diabetic retinopathy. They had weekly PRP treatments i...
Eligibility Criteria
Inclusion
- patients with severe NPDR or early PDR without macular edema
- best-corrected visual acuity (BCVA) of 20/25 or better
- patients who were followed up for at least 6 months after the first PRP.
Exclusion
- patients with retinal or choroidal diseases except diabetic retinopathy
- contraindications to fluorescein angiography (FA) or bevacizumab
- patients who had previous treatments including anti-angiogenic medications and laser photocoagulation
- patients with previous vitrectomy
- patients with uncontrolled hypertension, a recent myocardial infarction or cerebral vascular accidents.
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2013
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01504724
Start Date
August 1 2011
End Date
August 1 2013
Last Update
December 25 2013
Active Locations (1)
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1
Dong Ho Park
Daegu, South Korea, 700-721