Status:
COMPLETED
Early Nurse Detection and Management of Delirium
Lead Sponsor:
Penn State University
Collaborating Sponsors:
Vanderbilt University Medical Center
Harvard University
Conditions:
Delirium Superimposed on Dementia
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
Delirium (acute confusion) is common and costly in persons with dementia, resulting in longer hospital stays, more complications, and greater functional decline. This research tests the use of the ele...
Detailed Description
Delirium is an acute, reversible change in mental status that occurs in over 40% of persons with dementia. Delirium superimposed on dementia (DSD) leads to increased mortality, increased costs, nursin...
Eligibility Criteria
Inclusion
- Persons with dementia will be included if they: a) are on one of the selected medical-surgical units and are age 65 years or older; b) have been hospitalized less than 48 hours; and c) meet the criteria for dementia. The study will include minorities and women.
Exclusion
- Persons with dementia will be excluded if they have any significant neurological or neurosurgical disease associated with cognitive impairment other than dementia (due to confounding with dementia or DSD), such as:
- Lewy Body Dementia
- Huntington's disease
- Sormal pressure hydrocephalus
- Seizure disorder
- Subdural hematoma
- Head trauma
- Known structural brain abnormalities
- Nonverbal and unable to communicate due to severe dementia (MMSE=0)
- Aphasia
- Intubation
- Terminal illness (since interviews are required for the study).
- This study will not exclude persons with pre-existing delirium.
- In addition, subjects will not be excluded on the basis of race or gender.
Key Trial Info
Start Date :
April 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2015
Estimated Enrollment :
391 Patients enrolled
Trial Details
Trial ID
NCT01505257
Start Date
April 1 2010
End Date
February 1 2015
Last Update
October 26 2017
Active Locations (2)
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1
Mount Nittany Medical Center
State College, Pennsylvania, United States, 16801
2
Vanderbilt University Medical Center
Nashville, Tennessee, United States