Status:

COMPLETED

Biomarkers in Samples From Patients With B-Cell Acute Lymphoblastic Leukemia

Lead Sponsor:

Eastern Cooperative Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Leukemia

Eligibility:

All Genders

15-65 years

Brief Summary

RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This research study is studying...

Detailed Description

OBJECTIVES: * To identify microRNAs that behave as oncogenes or as tumor suppressor genes in B-lineage acute lymphoblastic leukemia (ALL) in vitro and in vivo. * To examine if single microRNA or sign...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Samples from patients enrolled on ECOG-2993
  • Samples from patients with recurrent cytogenetic abnormalities other than BCR-ABL, including MLL/AF4, E2A/PBX1, and TEL/AML1
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    January 6 2012

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    February 6 2012

    Estimated Enrollment :

    186 Patients enrolled

    Trial Details

    Trial ID

    NCT01505699

    Start Date

    January 6 2012

    End Date

    February 6 2012

    Last Update

    May 17 2017

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