Status:
COMPLETED
Impact of Clopidogrel Dose Adjustment According to Platelet Reactivity Monitoring in Patients With High on Treatment Platelet Reactivity Undergoing Percutaneous Coronary Intervention
Lead Sponsor:
Assistance Publique Hopitaux De Marseille
Conditions:
Acute Coronary Syndromes
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Acute coronary syndromes are related to the development of a platelet derived thrombus on a ruptured coronary atheroma. Use of dual antiplatelet therapy aspirin-thienopyridine a significantly reduced ...
Eligibility Criteria
Inclusion
- Subject in front of benefited from a coronary angioplasty with setting-up of an endoprothese for a SCA
- Subject agreeing to be followed over a period of 1 month
- Subject agreeing to participate in the research and having given its signed enlightened consent
Exclusion
- Subject minor or of more than 75 years old
- Subject presenting a rate of red blood cells \< 4 G/l or a thrombocytopenia \> 100 000 / mm3 plaques
- unaffiliated Subject in a benefit system
- pregnant or breast-feeding Woman: a pregnancy test will be realized in a systematic way, as well as a stake under contraception of the women old enough to procreate
- Intolerance or allergy in the aspirin or in the clopidogrel
- Pathology associated with a life expectancy 6-month-old subordinate according to the investigator
- haemorrhagic Syndrome threatening the vital forecast, the intra-cranial tumor
- Contraindication in one of the medicines of the study
- Severe hepatocellular incapacity
- Fibrinolyse meadow or hospital intra
- Ceaseless ventricular arrhythmias
- State of cardiogenic shock
- History of cerebral vascular accident
- Weight lower than 60 kg
Key Trial Info
Start Date :
July 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
187 Patients enrolled
Trial Details
Trial ID
NCT01505790
Start Date
July 1 2011
End Date
May 1 2012
Last Update
May 23 2012
Active Locations (1)
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1
Assistance Publique Hopitaux de Marseille
Marseille, France, 13354