Status:

COMPLETED

The Effects of the Water Drinking Test on Intraocular Pressure

Lead Sponsor:

University of California, San Diego

Conditions:

Glaucoma

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

This clinical trial is designed to investigate the efficacy profile of the SENSIMED Triggerfish® during 24-hour IOP monitoring in patients with glaucoma or ocular hypertension, done three times at mon...

Detailed Description

The investigation will recruit male and female patients 18-80 years old and diagnosed with glaucoma or ocular hypertension requiring hypotensive ocular treatment. Up to 100 subjects will be enrolled i...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Subject is able to comply with the study procedures
  • 18-80 years old
  • Subjects diagnosed with glaucoma, based on presence of repeatable visual field loss and/or glaucomatous optic neuropathy based on masked review of optic disc stereophotographs and under ocular hypotensive treatment, or diagnosed with ocular hypertension, with an IOP of \> 22 mmHg at the screening visit and under ocular hypotensive treatment.
  • Subject has consented to be in the trial
  • Visual acuity of 20/80 or better
  • Ability to understand the character and individual consequences of the study
  • For women of childbearing potential, adequate contraception
  • Stable anti-hypertensive treatment regimen 4 weeks prior to the screening visit and throughout the study.
  • Exclusion criteria
  • Subjects with chronic kidney failure and chronic hear disease
  • Subjects with contraindications for wearing contact lenses
  • Severe dry eye syndrome
  • Keratoconus or other corneal abnormality
  • Conjunctival or intraocular inflammation
  • Eye surgery prior to and throughout the study, except prior uncomplicated cataract surgery and laser a minimum of 3 months prior to the screening visit.
  • Full frame metal glasses during SENSIMED Triggerfish® monitoring
  • Known hypersensitivity to silicone, plaster or ocular anesthesia (proparacaine)
  • Pregnancy and lactation
  • Simultaneous participation in other clinical studies
  • No patient will be allowed to participate in this trial more than once

Exclusion

    Key Trial Info

    Start Date :

    August 1 2011

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    April 30 2013

    Estimated Enrollment :

    23 Patients enrolled

    Trial Details

    Trial ID

    NCT01507584

    Start Date

    August 1 2011

    End Date

    April 30 2013

    Last Update

    September 11 2019

    Active Locations (1)

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    Hamilton Glaucoma Center, UCSD

    La Jolla, California, United States, 92093