Status:
UNKNOWN
Time-lapse Evaluation of Human Embryo Development in Single Versus Sequential Culture Media - a Sibling Oocyte Study
Lead Sponsor:
Bahceci Health Group
Conditions:
In-vitro Fertilization
Eligibility:
FEMALE
18-39 years
Brief Summary
Current human IVF technology employs two strategies with respective culture media for embryo development; 'let the embryo choose' (utilizes single step media) and 'back-to-nature' (utilizes sequential...
Detailed Description
Maintaining optimal embryo development during in vitro culture is a key element in assisted reproduction treatments. Whether the concept of mimicking in vivo environment is a 'must' in order not to co...
Eligibility Criteria
Inclusion
- Cycles which have gone through egg retrieval procedure between March to November 2011 were included into the study.There was no restriction on the number of previous trials and/or sperm source.
Exclusion
- The maximum number of retrieved oocytes was restricted to 12 and the minimum to 2, as the former was the capacity of one dish (EmbryoSlide™) in which oocytes/embryos could be placed and the latter was the minimum number to be able to make a comparison between groups. Women who were older than 40 years of age were excluded in order to minimize the impact of increased risk of aneuploidy on the results.
- Cycles in which oocytes/embryos have been subjected to biopsy were also excluded due to the potential risk of delayed embryo development in such cases (Kirkegaard et al., 2011).
- Furthermore, cycles in which diagnosis of infertility was endometrial factor were not included since such aetiology could negatively affect implantation despite good embryo development.
Key Trial Info
Start Date :
March 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2012
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01507883
Start Date
March 1 2011
End Date
January 1 2012
Last Update
January 11 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Bahceci Fulya IVF Clinic
Istanbul, Turkey (Türkiye)