Status:
COMPLETED
DAHANCA 25B: Progressive Resistance Training as Intervention for Regaining Muscle Mass After Radiation Therapy in Patients With HNSCC
Lead Sponsor:
Danish Head and Neck Cancer Group
Conditions:
Head and Neck Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Head and neck cancer patients often experience a critical weight loss of around 10% following radiation therapy. Of this up to 70% is muscle mass and is an independent predictor of mortality, lowers m...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Histologically diagnosed with squamous cell carcinomas of the larynx (no glottis stage I+II), pharynx, oral cavity or in lymph nodes from an unknown primary tumour (stage I-IV and tumour node metastasis (TNM) classification, UICC, Geneva, 1987)
- Terminated curative radiotherapy treatment with/without chemotherapy;
- No metastases
- Complete tumour remission
- No current or previous malignancies that could prevent participation and training
- No excessive alcohol intake (men \> 21 and women \> 14 units/wk)
- No recent systematic resistance training or creatine ingestion (within 2 months)
- If woman, not pregnant
- WHO performance status of 0-1
- No psychological, social or geographical conditions that could disturb participation
- Written consent
Exclusion
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT01509430
Start Date
October 1 2011
End Date
April 1 2013
Last Update
November 29 2016
Active Locations (1)
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1
Dept. of Experimental Clinical Oncology
Aarhus C, Denmark, 8000