Status:
TERMINATED
Hyperinvasive Approach in Cardiac Arrest
Lead Sponsor:
Charles University, Czech Republic
Conditions:
Out-of Hospital Cardiac Arrest
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Prague out-of Hospital Cardiac Arrest (OHCA) study is a prospective randomized multicenter clinical study comparing use of prehospital intraarrest hypothermia, mechanical chest compression device, ext...
Detailed Description
Background: Out of hospital cardiac arrest (OHCA) has a poor outcome. Recent non-randomized study of ECLS (extracorporeal life support) in OHCA suggested further prospective multicenter studies to def...
Eligibility Criteria
Inclusion
- minimum of 18 and maximum of 65 years
- witnessed out-of-hospital cardiac arrest of presumed cardiac cause
- minimum of 5 minutes of ACLS performed by emergency medical service team without sustained ROSC
- unconsciousness (Glasgow Coma Score \< 8)
- ECMO team and bed-capacity in cardiac center available.
Exclusion
- OHCA of presumed non-cardiac cause
- unwitnessed collapse
- pregnancy
- sustained ROSC within 5 minutes of ACLS performed by EMS team
- conscious patient
- known bleeding diathesis or suspected or confirmed acute or recent intracranial bleeding
- suspected or confirmed acute stroke
- known severe chronic organ dysfunction or other limitations in therapy
- "do not resuscitate" order or other circumstances making 180 day survival unlikely
- known pre-arrest cerebral performance category CPC ≥ 3.
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 25 2020
Estimated Enrollment :
256 Patients enrolled
Trial Details
Trial ID
NCT01511666
Start Date
March 1 2013
End Date
October 25 2020
Last Update
March 15 2021
Active Locations (1)
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1
General Teaching Hospital
Prague, Czechia, 128 02