Status:
COMPLETED
Sevoflurane's Effect on Mitral Valve Annular Velocity in Cardiac Surgery
Lead Sponsor:
Konkuk University Medical Center
Conditions:
Valvular Heart Disease
Eligibility:
All Genders
20-65 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this study is to determine sevoflurane's dose-dependent effect on left ventricular (LV) function in cardiac surgery. The change of tissue Doppler imaging (TDI) of lateral mitral valve a...
Detailed Description
Following data would be determined after 10 min-exposure to each dosage of sevoflurane with 1.0, 2.0 and 3.0 inspired vol% (T1, T2 and T3, respectively) during remifentanil-based anesthesia (1.0 mcg/k...
Eligibility Criteria
Inclusion
- patients undergoing cardiac surgery
Exclusion
- low ejection fraction \< 50% in preoperative transthoracic echocardiography
- atrial fibrillation
- pacemaker
- pericardial and infiltrative myocardial disease
- mitral annular calcification, surgical rings, prosthetic mitral valves
- lateral left ventricular regional wall motion abnormality
- esophageal spasm,stricture, laceration, perforation, and diverticulum
- diaphragmatic hernia,
- history of extensive radiation to the mediastinum
- upper gastrointestinal bleeding
Key Trial Info
Start Date :
May 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01511991
Start Date
May 1 2009
End Date
May 1 2014
Last Update
February 24 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Konkuk University Medical Center
Seoul, Seoul, South Korea, 143-729