Status:

COMPLETED

Effects of High and Low Tidal Volumes on Arterial Oxygenation and Pulmonary Shunt During One-Lung Ventilation

Lead Sponsor:

The Cleveland Clinic

Conditions:

Postoperative Lung Injury

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The ideal tidal volume (TV) during one-lung ventilation (OLV) remains controversial. High tidal volumes may increase the incidence of postoperative lung injury after thoracic surgery. The investigator...

Eligibility Criteria

Inclusion

  • ASA I-III patients scheduled for lung resection surgery.

Exclusion

  • severe cardiovascular disease
  • severe alteration of the preoperative pulmonary function, with FEV1 70-120% predicted and FEV1/FVC ≥ 70% predicted considered to be normal.

Key Trial Info

Start Date :

June 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2009

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT01513018

Start Date

June 1 2009

End Date

September 1 2009

Last Update

January 20 2012

Active Locations (1)

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1

University of Debrecen, Medical and Health Science CenterDepartment of Anesthesiology and Intensive Care

Debrecen, Hungary, 4032