Status:
COMPLETED
Effect of Intranasal Oxytocin on Appetite and Caloric Intake in Men and Women
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Eating Behavior
Eligibility:
All Genders
18-45 years
Phase:
EARLY_PHASE1
Brief Summary
Exciting advances have led to the concept that hormones can modulate appetite and food intake. Oxytocin is a peptide hormone that is released in regions throughout the brain, including areas involved ...
Eligibility Criteria
Inclusion
- 18-45 years old
- BMI 18.5-24.9, 25-40
- Regular breakfast eater (at least 4 times per week)
- Stable weight within the past three months
Exclusion
- Psychiatric disease
- Use of psychotropic medications
- History of eating disorder
- History of excessive exercise within the last three months
- History of diabetes mellitus
- Active substance abuse
- Hematocrit below normal range
- Gastrointestinal tract surgery (including gastrectomy, gastric bypass surgery, and small or large bowel resection)
- History of cardiovascular disease (such as hypertrophic cardiomyopathy, valvular heart disease, coronary heart disease, or coronary artery spasms)
- Untreated thyroid disease
- Tobacco use
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2014
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT01513499
Start Date
January 1 2012
End Date
January 1 2014
Last Update
April 8 2019
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114