Status:
COMPLETED
Remote Ischemic Preconditioning in Neurological Death Organ Donors
Lead Sponsor:
Rutgers, The State University of New Jersey
Collaborating Sponsors:
Health Resources and Services Administration (HRSA)
The University of Texas Health Science Center at San Antonio
Conditions:
Organ Transplantation
Eligibility:
All Genders
6+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether application of lower limb remote ischemic preconditioning (RIPC) after determination of brain death improves donor stability, organ quality, organ yie...
Detailed Description
Study Design and Participants The RIPNOD trial was conducted from July 2011 to July 2014 as a prospective randomized trial in two OPOs (in New Jersey and in Texas) in the U.S. The funding organization...
Eligibility Criteria
Inclusion
- Neurological death donors in whom brain death determination is imminent
- First person consent or next of kin consent for research
- Donors \>=6 years of age
- Organ recovery not expected within 6 hours of consent.
- Both sexes and ethnicities.
Exclusion
- Donation after cardiac death donors (DCD)
- Live organ donors
- No first person consent and next of kin decline research consent
- Donor Age \< 6 years
- Lower extremity trauma or recent amputation
- Tissue only donors
Key Trial Info
Start Date :
July 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
321 Patients enrolled
Trial Details
Trial ID
NCT01515072
Start Date
July 1 2011
End Date
April 1 2015
Last Update
December 19 2018
Active Locations (2)
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1
Rutgers, The State University of New Jersey
Newark, New Jersey, United States, 07101
2
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States, 78229