Status:
TERMINATED
MRI-Guided Laser Induced Thermal Therapy
Lead Sponsor:
Rutgers, The State University of New Jersey
Collaborating Sponsors:
Rutgers Cancer Institute of New Jersey
Conditions:
Malignant Glioma
Eligibility:
All Genders
18+ years
Brief Summary
Does MR-guided laser interstitial thermal therapy (MRgLITT) prior to chemotherapy and/or radiation give patients a beneficial increase in overall survival? Laser induced thermal therapy (LITT) is a mi...
Detailed Description
Laser induced thermal therapy (LITT) is a procedure for destroying tissue through generation of heat. When used in conjunction with fiberoptic applicators, it offers an excellent means of minimally in...
Eligibility Criteria
Inclusion
- Subjects that have/will undergo MRgLITT for inoperable brain tumor.
- Tumor size \< 3cm in transverse diameter for each planned applicator placement.
- Tumor size \< 4 cm in largest dimension.
- Lesion(s) are clearly defined on pre-therapy contrast enhanced MRI scans as determined by the treating surgeon.
- Karnofsky Performance Scale score \> 70.
- ECOG performance status of 2 or better.
- Biopsy proven histologic diagnosis of malignant glioma.
Exclusion
- Patients with co-existing medical conditions with life expectancy \< 1 year.
- Patients having received pre-ablation chemotherapy and/or radiation to lesion.
Key Trial Info
Start Date :
August 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT01515085
Start Date
August 1 2011
End Date
June 1 2012
Last Update
May 22 2014
Active Locations (1)
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1
Robert Wood Johnson University Hospital
New Brunswick, New Jersey, United States, 08901