Status:
COMPLETED
The Effect of Music Periodicity on Interictal Epileptiform Discharges
Lead Sponsor:
Medical University of South Carolina
Conditions:
Rolandic Epilepsy
Benign Childhood Epilepsy With Centrotemporal Spikes
Eligibility:
All Genders
5-12 years
Phase:
NA
Brief Summary
The purpose of this study is to determine if having children listen to the music of Wolfgang Amadeus Mozart (Sonata for Two Pianos in D Major, K. 448) will lessen the amount of spike discharges on his...
Eligibility Criteria
Inclusion
- Female or male with BCECTS clinical history, and at least one seizure, as defined by the International League Against Epilepsy.
- EEG consistent with features of BCECTS: centrotemporal (rolandic) interictal spike discharges (ISDs) with otherwise normal background interictal EEG
- Screening neurological examination normal (by PI or other pediatric neurologist in the Division of Pediatric Neurology at MUSC)
- Age 5-12 years, inclusive
- On less than or equal to 2 anti-epileptic drugs (AED) \[Range 0-2 AEDs\]
Exclusion
- Currently taking Clonazepam or other Benzodiazepines
- Inability to complete 12 hour admission and comply with study protocol
- Prohibited Therapy or Activities During Study Period: Use of computer or video games. Viewing of video tapes will be prohibited due to potential effect of music in videos on underlying process of study.
- Due to the confounding factor of probably suppression of IEDs after a clinical seizure, any subject experiencing a seizure of any duration 24 hours prior to beginning the study will be excluded from the study.
- For any subject experiencing a seizure during the study, data analysis will cease from that point onward.
Key Trial Info
Start Date :
February 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT01515436
Start Date
February 1 2004
End Date
December 1 2007
Last Update
January 24 2012
Active Locations (1)
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1
Medical University of South Carolina
Charleston, South Carolina, United States, 29425